ea0081p165 | Pituitary and Neuroendocrinology | ECE2022
Refardt Julie
, Imber Cornelia
, Nobbenhuis Rianne
, Clara Odilia Sailer
, Haslbauer Aaron
, Vogt Deborah
, Berres Manfred
, Winzeler Bettina
, Bridenbaugh Stephanie
, Mirjam Christ-Crain
Introduction: Hyponatremia is the most common electrolyte disorder and the syndrome of inappropriate antidiuresis (SIAD) is one of its main causes. However, treatment options for chronic SIAD-induced hyponatremia are inadequate. This is problematic because hyponatremia has been associated with neurocognitive deficits, although there is little data on its reversibility. We previously showed that the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin is a promising s...